According to the ICMART (International Committee Monitoring Assisted Reproductive Technologies) report presented at the annual ESHRE Congress in Istanbul in 2012, since 1978 and the birth of Louise Brown until 2012, more than 5 million children were born with assisted reproduction techniques.

The calculation is based on the number of procedures reported by 2008, and the assumption that over 1.5 million IVF/ICSI cycles are performed annually, so data from 2009-2011 which were not existing, were added.